Signal transduction and epigenetic regulation in neuronal and cancer cells
Research interests of this laboratory focus on signal transduction and epigenetic regulation of gene expression related to some fundamental biological questions: cell survival and apoptosis in normal and diseased cells, neuronal differentiation and development, drug addiction, and cancer. We are applying multidisciplinary approaches to addressing these fundamental questions. The research methods that we are using are a combination of techniques of molecular and cell biology, DNA arrays, RNA interference, and mass spectroscopy-based proteomics, protein chemistry, and chemical biology. The potential findings from this research may have broad implications in many fields such as cancer biology, drug addiction, neurodegenerative disorders, neuronal development, and targeted therapy. |